The FAKTR PodcastOctober 06, 202300:31:58

#64 - Immune Reboot with Dr. Robert Silverman, Part 1

Immune Reboot with Dr. Robert Silverman


While it may seem like the darkest days of the COVID pandemic are behind us, even now...as we are nearing the end of 2023 you will be hard-pressed to find one healthcare provider who hasn't encountered a patient with the myriad of strange symptoms associated with "long COVID."From lingering fatigue and neurological symptoms to chronic pain and an increase of autoimmune disease diagnoses, we are just now beginning to realize the long-term impacts of the virus on global health and longevity.

So what do you do?How do you help your post-COVID patients boost their immune systems and get back on track towards the health and vitality they once enjoyed?If you've ever asked yourself these questions, you're in luck. This training will definitely provide some answers as we take a deep dive into the science behind the rise in autoimmunity and increased inflammatory status following recovery from COVID-19 infection.

Learn more about this episode on the new FAKTR Podcast website here >>View the recorded webinar training here >>Learn more about the new Chiropractic Acupuncture 100hr Certification Program here >>

Enroll in the FREE FAKTR Webinar Here (1hr of CE credit offered in many US states): https://tinyurl.com/FAKTR-webinar-55
LINKS:
Submit your questions for an upcoming Q&A episode here: https://2earrqgh.paperform.co
Want to stay informed about upcoming events, special offers, new products, courses and more? Click the link below to get on our email list (and get a free gift from FAKTR when you sign up):
https://faktrperformance.com/join-the-list-5776

CONNECT WITH US ON SOCIAL MEDIA:
FACEBOOK: https://www.facebook.com/FAKTRconcept
INSTAGRAM: https://www.instagram.com/FAKTREDUCATION
LINKEDIN: https://www.linkedin.com/showcase/faktr

[00:00:00] Hi guys, welcome to another episode of the FAKTR Podcast.

[00:00:18] I'm your host, Jessica Riddle.

[00:00:20] If this is your first time tuning in, welcome and thank you for listening.

[00:00:25] Today we kick off a new two-part training titled Immune Reboot, a guide to maximizing

[00:00:31] immunity and optimizing vitality featuring guest speaker Dr. Robert Silverman.

[00:00:37] While it may seem like the darkest days of the COVID-19 pandemic are behind us, even now,

[00:00:43] as we are nearing the end of 2023, you'll be hard-pressed to find one healthcare provider

[00:00:49] who has an encounter to patient with the myriad of strange symptoms associated with long

[00:00:55] COVID.

[00:00:56] From lingering fatigue and neurological symptoms, to chronic pain and an increase of autoimmune

[00:01:02] disease diagnoses, we are just now beginning to realize the long-term impacts of the virus

[00:01:08] on global health and longevity.

[00:01:11] So what do you do when the patient is standing in front of you with these strange symptoms?

[00:01:17] How do you help them boost their immune systems and get back on track towards the health

[00:01:22] and vitality that they once enjoyed?

[00:01:25] If you've ever asked yourself these questions, you're in luck.

[00:01:29] This training will definitely provide some answers as we take a deep dive into the science

[00:01:34] behind the rise in autoimmune and increased inflammatory status following recovery from

[00:01:40] COVID-19 infection.

[00:01:43] Dr. Silverman will also provide actionable steps you can take to help your patients boost

[00:01:48] their immunity so that they can be more resilient to the next big super bug.

[00:01:53] And who better to discuss this important topic than someone who has dedicated their career

[00:01:58] to educating the masses about the importance of proper nutrition and gut health.

[00:02:03] Dr. Robert Silverman is a chiropractor in clinical nutritionist, best-selling author,

[00:02:09] renowned presenter, and the founder and CEO of Westchester Integrative Health Center.

[00:02:15] He serves on the advisory board for the functional medicine university, is a chief clinical

[00:02:19] consultant for KBMO, diagnostics, and Arcania laser LTD and holds a science board position

[00:02:26] with Nutridine.

[00:02:28] With over 23 years of clinical experience, Dr. Silverman has considered a thought leader

[00:02:33] in his field and has contributed to several studies in peer-reviewed journals and other mainstream

[00:02:38] publications.

[00:02:40] This is one episode you'll definitely want to listen to more than once.

[00:02:45] So go ahead and hit that download button, let's cue the intro music and get started.

[00:02:59] Thanks so much, Jessica.

[00:03:00] It's a pleasure to be here.

[00:03:01] Send your regards to your wonderful husband, Dr. Todd.

[00:03:05] This is a great job with factor, big shout out.

[00:03:08] Most people ask, where did it come up with this idea of why right the book?

[00:03:13] And it's a great question.

[00:03:15] I live in New York, I'm right outside New York City, I'm 30 minutes.

[00:03:18] I did happen to grow up in New York City and in March of 2020 when COVID hit, it was six

[00:03:25] particular blocks from where I lived.

[00:03:28] So my neighbor is my patients, my friends, some family members, contracted COVID and I was

[00:03:35] looking for answers searching to find the guy, the girl.

[00:03:38] The expert, the guru, if you will.

[00:03:41] And they were nowhere to be found, unfortunately.

[00:03:44] There was nobody in our space or nobody in this space that said that they were the immune

[00:03:49] experts.

[00:03:50] We all touch upon it, we all integrated.

[00:03:53] It certainly has grown in the last three years, if you will.

[00:03:57] There was no place to go.

[00:03:58] So I started a document, research, really make a real clear stew, if you will, of what was

[00:04:04] needed.

[00:04:05] The purpose was to document what we could do as a playbook to move on, because our immune

[00:04:13] systems are working for us 24, 7, 365.

[00:04:17] Our immune system represents our protection from the hostile outside world of bacteria,

[00:04:21] viruses, toxic chemicals, intestinal microbiome, stress factors and of course trauma.

[00:04:28] It generally does a complain or speak up unless it's neglected, it has been mistreated.

[00:04:34] It just does its job quietly behind the scenes, but when our immune system is challenged,

[00:04:39] it typically jumps into action to defend us and help orchestrate the repair of damaged parts.

[00:04:45] We each possess a unique immune system, truly based on a genetic history and the exposures

[00:04:51] we have encountered, starting from our earliest experiences in the womb.

[00:04:55] The ability of our immune system to function at higher levels over decades of our life depends

[00:05:00] upon how we have treated it, how we take care of it.

[00:05:04] Like every cell of our body, the immune cells need to be properly fed, exercise, rested

[00:05:10] and supported with a healthy lifestyle.

[00:05:13] What the immune system needs for optimum function is different, truly from person to person.

[00:05:18] This really speaks to the idea of individualizing and personalizing our care for our patient

[00:05:24] base.

[00:05:26] So you'll learn in this presentation how the immune system can be rebooted, to improve its

[00:05:30] ability to serve your needs without complaining.

[00:05:33] When I use the term complaint as it relates to immune system function, I'm talking about

[00:05:37] how it talks back with us with inflammation, allergies, chemical and food sensitivities

[00:05:42] and reduced resilience.

[00:05:43] So why is that so important people ask?

[00:05:46] Well the function of immune system has been terminated over the past two decades and with

[00:05:51] an emphasis over the last three years to be a major factor that determines not only

[00:05:56] overall health and disease risk to both infectious and non-infectious diseases but also

[00:06:01] our life expectancy, I.E. long, Jebady.

[00:06:04] Yes, the function of a person's immune system as they age has been found to predict how long

[00:06:10] they will live.

[00:06:11] When you apply it in your life, you'll be learning this in this presentation which can make

[00:06:16] a big difference in both your meat and long-term health.

[00:06:20] One of my quotes I love to use constantly is you can't control the virus.

[00:06:26] You can only control the host.

[00:06:28] I cannot control the virus for my patients.

[00:06:31] I can't filter the invisible out of the air.

[00:06:34] We do our filters as things that we can do but what I can do and what we can share with all

[00:06:38] our patients, friends and family is how to make them in a hospital post for a viral bacteria

[00:06:45] and a fungal infection.

[00:06:47] Obesity, a port entail.

[00:06:49] 42% of people gain more weight than intended over the past year because of COVID.

[00:06:55] Some of these studies show a 29-pound gain on average 10% of the population of a COVID gain

[00:07:01] 50 pounds.

[00:07:03] 54% gain weight due to COVID restrictions, 54% exercise less and 68% because of the stress

[00:07:10] is snacking more.

[00:07:12] So COVID, if you had COVID, you had a higher incidence over obesity, if you had obesity,

[00:07:17] you had a higher positivity rate for COVID-19.

[00:07:23] Interesting that if you have COVID, you're going to see a change in your overall onset

[00:07:28] of increased normal heart rates.

[00:07:31] About 79 days you had increased heart rate.

[00:07:34] That's a long period of time.

[00:07:35] 32 days it took to get back to the exercise level before, once you pop a negative test.

[00:07:41] What I think which may be the most detrimental or deleterious effect of COVID was it took 24 days

[00:07:48] to get back to normal sleep patterns.

[00:07:51] So COVID-19 is linked to sleep and problems and fatigue.

[00:07:54] We just talked about that but these sleep disorders, interesting enough, maybe due to inflammatory

[00:07:59] responses or blood brain barrier dysfunction.

[00:08:02] The sleep disturbance also may be seen in chronic fatigue syndrome, which will say a parallel

[00:08:08] increase in the positivity of COVID-19.

[00:08:13] So mobility issues, why did I put this in?

[00:08:15] Well, car practice deal with mobility.

[00:08:16] We do functional movement assessments.

[00:08:18] We do functional movement screens.

[00:08:20] People over 50 had double the chance of mobility issues post COVID and it was shown in their

[00:08:25] participation in physical activities or worsening ability to engage in household activities.

[00:08:32] Talked about this just a little before about the long term effect that I really put it

[00:08:36] in and I wanted to mention it again was sleep patterns.

[00:08:40] Studies have shown that one night of loss of good quality sleep has a detrimental effect

[00:08:45] on your brain.

[00:08:46] You sleep, your brain goes to 40% of its size.

[00:08:51] It squeezes like a sponge or this metabolic waste.

[00:08:55] So if you don't have the animal time to do that, you can't detox your brain.

[00:08:59] You're not going to, if you will, think straight the next day 24 days of average sleep

[00:09:05] patterns after a positive test.

[00:09:08] So clearly we want to do the best we can to avoid having a positive test but once we do,

[00:09:13] we want to work within John Rauh of getting people back healthy and their immune system

[00:09:19] rebooted as quick as possible.

[00:09:21] Obviously, we're mostly if not all chiropractors.

[00:09:24] So the prevalence of low back pain did not change at the first few months of COVID-19

[00:09:29] pandemic but low back pain induced impairment and daily activities in pain intensity

[00:09:34] was higher when compared to before the pandemic.

[00:09:38] I said earlier, you're only as young as your immune system.

[00:09:41] And the reason I'm really hammering this point home is we have some very famous docs

[00:09:45] doing a great job releasing longevity books.

[00:09:49] This year, 2023 is the talk about longevity.

[00:09:53] The matching of life and health span.

[00:09:55] You don't want to live to 80 if you only have 40 years of a healthy lifespan.

[00:09:58] And you want to live to 80, especially if you have a good health span.

[00:10:04] You're only as young as your immune system.

[00:10:07] So we can talk about longevity all we want but if we have a break, a barrier, a breach in

[00:10:14] our immune system, that's going to show a tremendous mark against decreasing in our

[00:10:19] health span and our longevity.

[00:10:22] COVID also had a biological aging effect on many patients.

[00:10:26] It was in accumulation of epigenetic aging from COVID-19 which contributed to

[00:10:30] post COVID-19 syndrome amongst survivors.

[00:10:35] Tell them your shortnings, they showed a consistent biological aging,

[00:10:39] increased in post COVID-19 population.

[00:10:42] Tell them years are the fuse to the dynamite.

[00:10:45] So when you shorten your telemere, you're basically shortening your life.

[00:10:49] Tremendous interaction between COVID-19 and Sarcopenia, muscle mass is your longevity

[00:10:54] organ.

[00:10:55] Tau's University 1998 has stated that the loss of muscle mass is the first sign of aging.

[00:11:01] So long COVID which we're going to go through in detail shows an increase in

[00:11:06] C-reactoprotein specific blood markers TNF alpha and the interlucans in Farritan which

[00:11:11] are all inflammatory which can lead to fatigue and dyspnea.

[00:11:15] Also, long COVID leads to malnutrition.

[00:11:19] These are all biomarkers that feed unfortunately the loss of muscle mass I.E.

[00:11:24] Sarcopenia.

[00:11:25] So long COVID leads to Sarcopenia, Sarcopenia leads to a higher incidence of long COVID.

[00:11:31] This is one of the best studies that I've seen.

[00:11:33] I really made a point of this in my book again in a few pages because the influence

[00:11:38] of nutritional and takes in Japan into U.S. really spoke to where we as Americans are

[00:11:45] and where we lack in health.

[00:11:47] COVID-19 cases, there were 12 times higher in the U.S. than Japan times.

[00:11:53] Death was 17.4 times higher in the U.S. than the Japanese.

[00:11:57] The prevalence of obesity in American men was 7.4 times greater than Japanese men.

[00:12:03] American women 10 times greater than their counterparts.

[00:12:06] Take a look at the diet when it was analyzed, we as Americans consume more saturated fat,

[00:12:11] considerably less omega-3s and we much more beef to the tune of about 400 percent

[00:12:18] of grain fed beef and sugar and sweetness to the tune of 235%.

[00:12:24] The American consumes 160 pounds of sugar per year, 146 pounds of wheat,

[00:12:31] me included in 142 pounds of artificial sweetness.

[00:12:36] The Japanese on contrast eat 45 percent more fish, slightly more rice, not as much as you

[00:12:44] would think 11.5 percent and about 55 percent more TRI e-grain T.

[00:12:49] e-gc g-g-g-t the active ingredient that's critical for green teas medicinal facts

[00:12:55] has been shown to block the dock of spike proteins on our ACE2 receptor sites

[00:13:03] better than any drug or nutritional supplement.

[00:13:14] At Southeast Professional Education Group, we are incredibly selective about the courses we host

[00:13:20] on our online learning platform. We only want to offer our students the best, most dynamic

[00:13:26] evidence-based courses and because of this we only launch new courses a few times each year.

[00:13:32] We are unapologetically selective so I am beyond excited to announce that new courses have just

[00:13:37] launched and registration is now open for our chiropractic Acupuncture 100 hour certification program.

[00:13:44] In this hybrid course format you'll complete a mixture of self-paced virtual course work

[00:13:49] and attend four live hands-on sessions in beautiful West Palm Beach Florida. Not only does

[00:13:54] this course prepare you to add acupuncture to your treatment offerings, it also fulfills the

[00:13:59] requirements to qualify you to sit for the NVCE's Acupuncture Board exam. You can register for

[00:14:05] the full program or choose to only complete specific course modules that interest you.

[00:14:10] Learn more at the acupuncture link in our show notes or visit online.sports-seminar.com for details.

[00:14:21] So let's really get into a conversation now. Let's be conversationalists.

[00:14:25] Let's recognize the possible rise in order immunity and increase inflammatory status following

[00:14:31] recovery from COVID-19 infection. Taking you look at this slide, the cross-reactive patterns

[00:14:36] between SARS-CoV-2 proteins and autoimmune target proteins may play a role in the systemic

[00:14:41] inflammatory response from COVID-19 leading to the development of autoimmune diseases,

[00:14:47] post-infection, insesceptible subgroups or potentially playing a role in the severity of COVID-19

[00:14:53] illness. So when you take a look at this SARS-CoV-2 damage to GI and a tight junction,

[00:14:59] so the takeaway here and if there's one thing, I'm a gut guy. SARS-CoV-2 damages the integrity of

[00:15:05] the gut barrier. It also damages your skin, your nervous system, IE or brain, thyroid, joint,

[00:15:13] muscle and cellular components. So SARS-CoV-2, when allowed in the body, really let us down a slippery

[00:15:21] slope towards autoimmune. So what is the trigger for autoimmune? Well, we have some basic

[00:15:27] ideas of nutrition genetics, chemicals in ultraviolet light exposure, but the two big things that are

[00:15:33] really hurting us now are the COVID infection which damages our microbiota or our ecosystem inside

[00:15:39] our gut. So when you look at the virus such as SARS-CoV-2, you realize a can trigger a strong

[00:15:45] activation in immune system. The appearance of typical clinical manifestation such as myalgia,

[00:15:51] myocitis, chronic fatigue, sleep disturbances and neurological manifestations, cognitive impairment,

[00:15:57] memory loss, all of which have been reported in SARS-CoV-2 infections. So then you would see

[00:16:03] the appearance of auto antibodies which are antibodies that attack our own structure,

[00:16:09] which may lead to the development of autoimmune diseases, especially in genetically predisposed

[00:16:14] subjects. Therefore the current COVID-19 pandemic endemic indeed fulfilled almost all the major

[00:16:22] and minor criteria for autoimmune inflammatory syndrome induced by all these adjuvids. So therefore

[00:16:29] this took you through a flow chart of SARS-CoV-2 infection, ultimately leading you with autoimmunity.

[00:16:35] For carapractors what does that mean? Well autoimmunity is rheumatoid arthritis.

[00:16:40] autoimmunity carapractors, colleagues also means osteoarthritis. Myousa, muscle pain,

[00:16:48] people may be coming in and making complaints or having complaints of these conditions

[00:16:53] and the root cause could simply be COVID-19 a post-positive test. So the immune system provides

[00:17:01] three levels of defense against disease causing organisms. Number one, the barrier system,

[00:17:06] it prevents entry. It does so with skin, skin and mucus membranes. When you look at your skin,

[00:17:11] everybody knows what skin looks like. It's longest, largest, orgin in the body. Everybody knows

[00:17:17] when they cut their skin that they can simply put a bandaid on it to protect it. They cut their

[00:17:21] skin too much. They can have stitches to close up the gap. That said, when you have a hole in

[00:17:28] your gut we can see it. Patients can't see it. They're not that quick to want to patch the hole in

[00:17:35] their gut epithelium. mucus membranes like stomach acids, digestive enzymes all apart of your first

[00:17:42] part of immune system, beneficial bacteria in your gut like your microbiota, part of your beneficial

[00:17:48] bacteria. It has been postulated that the first time the outside world meets the inside world

[00:17:54] is when something gets absorbed through your small intestine. And when it does so, it stimulates

[00:17:59] something that we're given a day one, which is our native immune system, or it's our general

[00:18:03] defense. A native immune system is a 365 24-7, security guards of our immune system. There are

[00:18:11] immune centenols. They are a neutrophils and macrophages, which engulf in destroy foreign invaders

[00:18:18] and damage cells. We want to balance between that and our adaptive and our acquired

[00:18:23] or specific defense, or acquired immunity. Why is acquired? Well, everybody knows Jessica has

[00:18:29] four children and I'm sure she popped on right now. She would say it's flu season. It's

[00:18:34] ear infection. Each one gets it when they go to school because they're acquiring immunity.

[00:18:39] They acquire immunity through their B and T cells. Their T cells come from their thymus. They have

[00:18:45] thymus glands. Now what's interesting about their thymus or our all-our-thymus is,

[00:18:50] is the first gland that goes through in volucia. In volucia means the shrinking of. Therefore,

[00:18:57] during our teenage years, our T cells shrink. So obviously when we reach 40-50,

[00:19:04] we're not as effective at T cell expansion. And typically 65 or 70, the thymus provides us no

[00:19:10] defense. When we look at our B cells, they come from our bone marrow. Those are our antibodies.

[00:19:16] They catalog all different incidences with foreign invaders like viruses, bacteria,

[00:19:23] parasites and fungi. They are called IGE, which is an acute allergic reaction. IGA,

[00:19:30] which occurs at the secretory levels, IGM, which is initial in IGG, which is the most

[00:19:37] profound, proficient antibody in the body. It can pass the discuss it's small and get it can pass

[00:19:45] through the placenta. Excuse me, you can get to the fetus, 75% of our antibodies are IGG.

[00:19:50] The in-atomyun system provides an immediate response for foreign targets with responses typically

[00:19:56] within minutes to hours. It consists of a number of soluble factors and proteins such as the

[00:20:01] verse set of cells, including macrophages, the endotic cells, and natural killis cells. The second

[00:20:07] branch of the immune system is the adaptive required immune system, which provides specific

[00:20:12] long-lasting immune responses. The adaptive and innate immune responses are linked. For example,

[00:20:19] dentrites cells are an important adaptive immune cell activator. Natural pillous cells and T cells

[00:20:26] are specific in that they overlap both the innate and the adaptive immunity. Therefore,

[00:20:31] ultimately, cells in both arms of the immune system are in development as potential cellular

[00:20:36] immunotherapies. Sital kind storm versus cytokindras. We all heard about the storm. That's

[00:20:42] when we have an over-expression of interlucence. One of the reasons that we get this proverbial

[00:20:48] storm is very simple that we are pre-inflamed. We already have a release of excessive amounts

[00:20:54] of interlucence because we are pre-inflamed. My mantra is a chiropractic, just to manage and

[00:21:00] modulate inflammation. And I think unfortunately it's very hard to do so with the environment

[00:21:05] and especially the food choices that our patients are exposed to. The idea of a cytokind drizzle

[00:21:12] is to drizzle outside. You're building up the water and then you get sick, like with COVID,

[00:21:18] which is a new, norally virus. First time seeing our history, if you will, at least SARS-CoV-2,

[00:21:26] and what happens that drizzle turns into a storm. So a normal immune response,

[00:21:32] inflammation, which is normal was supposed to get an inflammation. It's even normal sometimes

[00:21:37] to raise a fever. Then you have your native immunity. You go to specific immunity. You get to

[00:21:43] rezzolusia and you have a memory of it. This is a perfect normal response to infection.

[00:21:49] Unfortunately, our typical immune response to COVID was hybrid in that SARS-CoV-2

[00:21:55] had too much inflammation because it's we as adults started to high and it didn't shut down fast enough.

[00:22:02] It spilled over to a native immunity where we had less cells because we have a dysfunctional immune

[00:22:07] system because we're not a healthy population. Then we had the specific immunity, the acquired

[00:22:12] and adaptive immunity, virulent factors did not launch. Ultimately, we had a slow resolution

[00:22:18] in poor to no memory. So let's take that one step further. Let's look at the idea of viral infection

[00:22:24] COVID-19 and an immune response to the virus, which led to an over-expression of cytokines,

[00:22:30] which ultimately led to microbial metabolites, which led to mitochondrial dysfunction and disease,

[00:22:37] IE everybody felt real poor. As I used to like to say, everybody feels like crap. This

[00:22:46] immune imprinting, I pause every time I see it because I shake my head. It's called original

[00:22:50] antigen sin. Let me give you the definition and then we break it down what they're really trying

[00:22:56] to say. It's a phenomenon in which the body preferentially repeats its immune response

[00:23:00] to the first variant encounters, despite being alerted to a new variant. It has been stated

[00:23:06] that we are still taking a COVID-19 picture of 2020. So the first virus infection that we

[00:23:13] encountered, we took a picture. So now we all know viruses purposes to mutate and as variants.

[00:23:21] We're not able to take a new picture with our immune system for that variant because we've already

[00:23:26] imprinted the original virus. And now this is why you're seeing people getting infected whether

[00:23:32] the vaccinated or not, not going in that rabbit hole. Now you're seeing people get infected the

[00:23:37] second and third time because our immune system is not resilient. Our immune system is not adapted.

[00:23:43] Our immune system takes a picture and does an adapt. And that's because most Americans are not

[00:23:49] healthy to piggyback on that thought immune imprinting in long COVID. MIT and Harvard did

[00:23:54] join study. 112 patients neurological long COVID symptoms which meant inflammation of the brain

[00:24:02] with cognitive deficits. What was found was an undo-whelming amount of antibodies to COVID-19.

[00:24:08] In addition, an overwhelming amount of antibodies in response to other coronaviruses. So the

[00:24:14] coronavirus could look like the common cold and what was happening was we kept thinking that

[00:24:19] COVID-19 was the common cold. And we were not sending antibodies or proper strength of

[00:24:26] proper antibodies to help ourselves out. Therefore, the immune printing actually led us down

[00:24:32] a path of neurological long COVID. So again, buzzword, immune resilience. We wanted to everything

[00:24:41] in an everyday life in our caliopractic armamentarium to allow for immune resilience. There is no

[00:24:48] single blood test that tells us that we have COVID or long COVID. However, there is a litany of

[00:24:54] tests that can lead us to that conclusion. They all interlukan one beta, interlukan six,

[00:25:01] interlukan eight and TNF alpha. These overactivate a monocytes of macrophages are typically the

[00:25:08] likely source of this cytokine overproduction. What's the definition of long COVID? It's changed.

[00:25:14] Here's where we are now. The continuation or development of new symptomology three months after

[00:25:21] the initiation of SARS-CoV-2 infection and these symptoms lasting for at least two months

[00:25:26] with no other explanation. So some subphenotypes for long COVID. Number one, the subphenotype one,

[00:25:32] they are unfortunately your sickest patients. They had cardiac and renal involvement.

[00:25:37] Subphenotype two, patients with respiratory and commental sleep dysfunction and anxiety problems.

[00:25:44] Subphenotype three, patients with predominant neurological and musculoskeletal presentations,

[00:25:50] and the last one, subphenotype four, patients with just digestive symptoms. Huge takeaway,

[00:25:56] numbers, number factoid, estimates have long shown that long COVID caused the U.S. economy

[00:26:04] 3.7 trillion dollars in his growing every day. This compares with the great recession of 2007

[00:26:12] in 2009, unfortunately long COVID is still growing to the tune of about 28% of the population.

[00:26:19] UCLA researchers found that 30% of people treated for COVID developed past post-acute

[00:26:26] Sequoia of COVID-19, I.E. Long COVID. Long COVID, 90% of those with long COVID initially had

[00:26:34] very mild symptoms. So we always thought that long COVID meant that it was in a continuation

[00:26:39] of a real severe case of COVID-19. That's not the case because the study was robust

[00:26:45] in that it was 1.2 million people over 20 countries. Symptoms had an impact this severe and long

[00:26:52] trauma facts, mimicking, concussion and TBI. Women have a greater risk than men,

[00:26:58] and women have a greater risk over children to develop long COVID. BMI and female sex risk factors

[00:27:06] seem to be the given for long COVID symptomology. Taking the concept of long COVID,

[00:27:13] here was a study with 100,000 participants anywhere from 6 to 18 months after infection,

[00:27:19] 1 in 20 and 42% essentially 50% had not recovered. The symptoms in long COVID were

[00:27:26] replicents, palpitations, chest pain, and of course brain fog reduced mental activity.

[00:27:32] So many patients, many docs asked me how does long COVID exhaust the body? There's four factors

[00:27:39] that increase the risk. Number one, higher level of viral RNA during the infection. We're in a room.

[00:27:44] We're in a movie theater. There's 500 people and that has 500, 200 are sick.

[00:27:50] Larger RNA load. We're in the same movie theater with the same 500 people. The only two are sick.

[00:27:57] Obviously less of a chance of us being right next to them but also less of a load.

[00:28:02] Presence of order antibodies. Talk about that before those order antibodies or anybody's

[00:28:07] at attack ourselves and not foreign particles. This will blow your mind. The reactivation of a lot

[00:28:15] of dormant viruses, one in particular called Epstein Mar virus which is mononucleosis. At 18 months ago

[00:28:23] I started to run a lot of blood labs on a lot of my post-COVID patients and everybody had an elevation

[00:28:30] of a myriad of viruses, especially Epstein Bar. So Epstein Bar is obviously mononucleosis. There's a lot

[00:28:39] of fatigue. It has been stated that we know that there's fatigue associated with COVID-19.

[00:28:46] There's fatigue associated with Epstein Bar. It could be one of the other or the combination thereof.

[00:28:52] And type two diabetes. If you do any blood labs, blood sugar, insulin resistance,

[00:28:57] our all markers that probably are the most ruinuous to people's overall health.

[00:29:02] Long COVID patients have disrupted immune systems, viral and genetic material are better than

[00:29:07] intestines and lymph nodes. The reason it's embedded in the intestines is that viruses are

[00:29:13] shedered through the gut as I see before a conversation in the next 20 minutes.

[00:29:19] Circulatory system we see increased in cytokines, microscopic blood clots in the brain

[00:29:25] very typical cognitive impairment. 12 months following a acute COVID-19 infection there was an increased

[00:29:31] risk of an array of neurological sequela, like stroke cognitive memories, peripheral nerve,

[00:29:37] disorders migraine, musculoskeletal disorders, movement disorders mental health. So the conclusion was

[00:29:43] very simple. There's an increased risk of long-term neurological disorders in people who had COVID-19.

[00:30:01] That's it for today's episode. Be sure to tune in for the second segment of this two-part

[00:30:05] series where Dr. Silverman will discuss the long-term impacts of COVID-19 infection on the lung

[00:30:11] gut brain access and gut microbiome and the role of systemic inflammation in long-hollar COVID.

[00:30:19] We will also talk more about strategies for reducing inflammation, including diet supplements

[00:30:25] and lifestyle improvements as well as effective nutritional protocols for the Oma-Cron variant and immune

[00:30:31] support. You won't want to miss it episode 65 drops in two weeks. And be sure to visit our show

[00:30:38] notes for all of the freebies and special offers mentioned in today's episode as well as the link to

[00:30:43] the replay of our webinar if you're more of a visual learner. We've just launched our new website at

[00:30:48] factorpodcast.com so be sure to check out that link in our show notes so that you can visit the site

[00:30:54] and get caught up on any past episode you may have missed. You can subscribe to the factor podcast

[00:31:00] on Apple, Spotify, I Heart Radio or the podcast app that works best for you. Give us a five-star

[00:31:07] rating to help us grow the show and be sure to share your favorite episodes with a friend. We'll see you next time.

[00:31:39] Any of these upcoming live webinar dates coming up in the near future so you can join us live.

[00:31:43] And of course the biggest compliment we can receive is for you to help us spread the word to your friends,

[00:31:48] colleagues and classmates. You'll find all the important links as well as info about our sponsors

[00:31:53] in the show notes, so be sure to check it out.